The treatment of minimal change disease in adults.
نویسندگان
چکیده
Minimal change disease (MCD) is the etiology of 10%-25% of cases of nephrotic syndrome in adults. The mainstay of treatment for adult MCD, oral glucocorticoids, is based on two randomized controlled trials and extensive observational data in adults, and this treatment leads to remission in over 80% of cases. Relapses are common, and some patients become steroid-resistant (SR), steroid-dependent (SD), or frequently relapsing (FR). The data guiding the treatment of these patients are limited. Here, we review MCD in adults with particular focus on the evidence for immunosuppressive therapy in these patients.
منابع مشابه
The relation between end of induction minimal residual disease and different risk factors in patients with acute lymphoblastic leukemia
Background: Malignant disorder with B or T stem cell basis leads to development and continuation of acute lymphoblastic leukemia (ALL) due to aggregation of blast cells in bone marrow. The environmental, genetic, and demographic factors may influence the disease relapse. The objective of this study was to assess the relation between end of induction minimal residual disease and different risk f...
متن کاملPentoxifylline in the treatment of pigmented purpuric dermatoses: A randomized, controlled trial
Background and aim: Pigmented purpuric dermatoses are a group of chronic and recurrent skin diseases resulting from lymphocyte-mediated leakage of erythrocytes. No effective treatment has been suggested for these conditions. This study was performed to evaluate the efficacy of oral pentoxiphylline in the treatment of pigmented purpuric dermatoses.Materials and Methods: ...
متن کاملBCG vaccine and pulmonary tuberculosis
Tuberculosis (TB) is one of the most important public health problems in the world and has been declared as a global emergency by the World Health Organization (WHO) in 1993. Bacillus Calmette-Guérin (BCG) is one of the first developed vaccines to prevent TB. Unfortunately, BCG vaccine has had a limited duration of protection and has shown controversial and variable levels of efficacy, especial...
متن کاملLimberg flap treatment results in pilonidal sinus disease
Introduction: Pilonidal sinus disease is a chronic disease of sacrococcygeal region which is caused due to growth on hair in intergluteal region causing foreign body reaction and abscess formation. Different procedures are used to treat this condition surgically, which have their own complications, and recurrence rate. Rhomboid excision with Limberg flap is a method with minimal complicat...
متن کاملTest-retest reliability and minimal detectable change for center of pressure measures of postural stability in elderly subjects
Abstract Background: Postural instability has been identified as a potential precursor of falls in elderly subjects. Postural stability in quiet stance is commonly assessed with center of pressure (COP) measures. The purpose of this study was to determine testretest reliability and minimal detectable change (MDC) for the center of pressure (COP) measures in the elderly subjects. Met...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Journal of the American Society of Nephrology : JASN
دوره 24 5 شماره
صفحات -
تاریخ انتشار 2013